direct-acting相关论文
Hepatitis C virus treatment failure:Clinical utility for testing resistance-associated substitutions
The hepatitis C virus has a high mutation capacity that leads to the emergence of resistance-associated substitutions(RA......
Viral hepatitis represents a major public health hazard and is associated withsignificant global mortality. Over the las......
BACKGROUND In the last few years we have witnessed a revolution in the treatment of hepatitis C virus(HCV)infection.With......
Histopathology and the predominantly progressive,indeterminate and predominately regressive score in
BACKGROUND Histological changes after direct-acting antivirals(DAAs)therapy in hepatitis C virus(HCV)patients has not be......
Direct-acting antiviral agents(DAAs)for hepatitis C virus(HCV)infection are one of the major advances in its medical tre......
Hepatocellular carcinoma (HCC) is a common and deadly malignancy. The disease usually develops on a background of chroni......
Chronic infection with hepatitis C virus(HCV)is one of the leading causes of liver disease globally,affecting approximat......
针对海水液压介质的特点,对直动式海水液压溢流阀的关键技术问题进行了分析,设计了一种直动式水压溢流阀.该阀的额定压力为14MPa,额定......
Peginterferon alfa-2a for the treatment of chronic hepatitis C in the era of direct-acting antiviral
BACKGROUND: The availability of novel direct-acting antivirals(DAAs) represents a new era of curative hepatitis C virus(......
Some direct-acting antiviral agents for hepatitis C virus(HCV),such as telaprevir and boceprevir have been available sin......
The use of direct-acting antivirals(DAAs) to treat chronic hepatitis C has resulted in a significant increase in rates o......
AIM:Toevaluatedaclatasvirvstelaprevir,eachcombinedwithpeginterferonalfa-2a/ribavirin(pegIFN/RBV),intreatment-naivehepati......
To investigate how natural killer(NK)cells are affected in the elimination of hepatitis C virus(HCV)by sofosbuvir/ledipa......
BACKGROUND Regimens involving direct-acting antiviral agents(DAAs)are recommended for the treatment of infection with he......
Sustained virologic response to direct-acting antiviral agents predicts better outcomes in hepatitis
BACKGROUND Direct-acting antiviral agents(DAAs)are extremely effective in eradicating hepatitis C virus(HCV)in chronical......
Chronic hepatitis C,atherosclerosis and cardiovascular disease:What impact of direct-acting antivira
Hepatitis C virus(HCV)infection is associated with extrahepatic manifestations,among these there is an increased risk of......
Since the advent of direct acting antiviral(DAA)agents,chronic hepatitis C virus(HCV)treatment has evolved at a rapid pa......
Hepatitis C virus(HCV)infection represents one of the major causes of chronic liver disease,hepatocellular carcinoma and......
BACKGROUND The effectiveness of sofosbuvir/ribavirin (SOF/RBV) combination therapy, which is one of the 1st-choice thera......
Post Hepatitis C Cirrhosis in Sub-Sahara Kidney Transplant, Treated with Sofosbuvir/Ledipasvir: Repo
Background: Viral hepatitis C is a major public health problem in the world. The advent of direct-acting antivirals has ......
Importance of virological response in the early stage of telaprevir-based triple therapy for hepatit
AIM: To investigate the efficacy of virological response(VR) to telaprevir(TVR)-based triple therapy in predicting treat......
Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while he
AIM To determine whether successful treatment with direc tacting antivirals(DAA)is associated with improvements in hemog......
The host innate and adaptive immune systems are involved in nearly every step of hepatitis C virus(HCV) infection. In pa......
Predictors of Direct-Acting Antivirals Failure in Patients with Chronic Hepatitis C Virus in Ivory C
Context and Aim: Direct-acting antivirals are the therapeutic revolution in the management of viral hepatitis C, but oft......
Background: Recently, increases in the risk of Hepatocellular carcinoma (HCC) recurrence in patients with hepatitis C vi......
Background: Viral hepatitis C is the second leading cause of hepatocellular carcinoma after hepatitis B in Africa and To......
Hepatocellular carcinoma incidence post direct-acting antivirals in hepatitis C-related advanced fib
Background:Despite efficacy in HCV eradication,direct-acting antiviral(DAA)therapy has raised controversies around their......
Hepatitis C infection can lead to cirrhosis and hepatocellularcarcinoma and it is an important cause ofmortality and mor......
Hepatitis C virus(HCV) is a global challenge; 130-175 million are chronically infected. Over 350000 die each year from H......
Hepatitis C virus (HCV) was discovered 26 years ago.For decades, interferon-based therapy has been themainstay of treatmen......
Over the last years it has started a real revolution in thetreatment of chronic hepatitis C. This occurred for theavaila......
Hepatitis C virus(HCV) infection is one of the most common causes of chronic liver disease and the main indication for l......
The development of boceprevir and telaprevir was a major step forward in the treatment of chronic hepatitis C.In additio......
Daclatasvir plus asunaprevir in treatment-naive patients with hepatitis C virus genotype 1b infectio
AIM To assess daclatasvir plus asunaprevir(DUAL)in treatment-na?ve patients from mainland China,Russia and South Korea w......
Hepatitis B reactivation in patients receiving direct-acting antiviral therapy or interferon-based t
AIM To assess the incidence of hepatitis B virus(HBV)reactivation in patients receiving direct-acting antiviral agent(DA......
Direct-acting antivirals and hepatocellular carcinoma in chronic hepatitis C:A few lights and many s
With the introduction of direct-acting antiviral agents(DAA),the rate of sustained virological response(SVR)in the treat......
Hepatitis C virus(HCV)infection remains an important global health problem with chronic infection affecting approximatel......
challenge to overcome:Nonstructural protein 5A-P32 deletion in direct-acting antiviral-based therapy
Interferon(IFN)-based therapy for hepatitis C virus(HCV)infection has recently been replaced by IFNfree direct-acting an......
Facial and bilateral lower extremity edema due to drug-drug interactions in a patient with hepatitis
BACKGROUND New direct-acting antivirals(DAAs)-based anti-hepatitis C virus(HCV)therapies are highly effective in patient......
Treatment of hepatitis C virus(HCV)infection has evolved greatly through the recent decade.The availability of direct-ac......
BACKGROUND Direct-acting antivirals(DAAs)are recommended for the treatment of hepatitis C virus(HCV)infection in patient......
In recent years,significant progress in the antiviral treatment of chronic hepatitis C(CHC)has been made due to the deve......
Clinical efficacy of direct-acting antiviral therapy for recurrent hepatitis C virus infection after
BACKGROUND Recurrent hepatitis C virus(HCV)infection of transplanted liver allografts is universal in patients with dete......
Pancreatic fat and β-cell function in overweight/obesechildren with nonalcoholic fatty liver disease
AIM To analyze the associations of pancreatic fatwith other fat depots and β-cell function in pediatricnonalcoholic fat......
Myanmar is adjacent to India, Bangladesh, Thailand, Laos and China. In Myanmar, the prevalence of hepatitis C virus(HCV)......
Major advances have been made in the treatment of chronic hepatitis C virus(HCV) infection with the advent of direct-act......
Hepatitis C virus resistance to new specifically-targeted antiviral therapy:A public health perspect
Until very recently,treatment for chronic hepatitis C virus(HCV)infection has been based on the combination of two non-v......
Outcomes assessment of hepatitis C virus-positive psoriatic patients treated using pegylated interfe
AIM To evaluate the outcomes in biological treatment and quality of life of psoriatic patients with chronic hepatitis C(......